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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata2tm1.1Sac
targeted mutation 1.1, Sally A Camper
MGI:3628640
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gata2tm1.1Sac/Gata2tm1.1Sac involves: 129S1/Sv * 129X1/SvJ MGI:3639704


Genotype
MGI:3639704
hm1
Allelic
Composition		 Gata2tm1.1Sac/Gata2tm1.1Sac
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata2tm1.1Sac mutation (0 available); any Gata2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:108963 )
• homozygous mutant embryos are undergoing resorption by by E11.5

hematopoietic system
anemia ( J:108963 )
• display severe anemia at E10.5
• yolk sacs are completely devoid of detectable red blood cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory