All Phenotypes Adam1b<tm1Tba> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adam1b^tm1Tba
targeted mutation 1, Tadashi Baba
MGI:3628759

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adam1b^tm1Tba/Adam1b^tm1Tba	involves: 129S2/SvPas * C57BL/6	MGI:3629710

Allelic Composition	Adam1b^tm1Tba/Adam1b^tm1Tba
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam1b^tm1Tba mutation (1 available); any Adam1b mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:109221 )

• males and females are normal in behavior, body size and health condition; epididymal sperm are functionally normal in migration into the oviduct, biding the zona pellucida, and fusion with the egg, however testicular germ cells lack the Adam1b/Adam2 heterodimer and epididymal sperm show loss of ADAM 2

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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