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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt33a+
wild type
MGI:3629954
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Krt33aPlsh-2Btlr/Krt33a+ C57BL/6J-Krt33aPlsh-2Btlr MGI:3805299
ht2
 		Krt33aPlsh-3Btlr/Krt33a+ C57BL/6J-Krt33aPlsh-3Btlr MGI:3834211
ht3
 		Krt33aPlsh/Krt33a+ C57BL/6J-Krt33aPlsh MGI:3805297


Genotype
MGI:3805299
ht1
Allelic
Composition		 Krt33aPlsh-2Btlr/Krt33a+
Genetic
Background		 C57BL/6J-Krt33aPlsh-2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt33aPlsh-2Btlr mutation (0 available); any Krt33a mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
shiny fur ( J:137499 )
• the hair coats of mice heterozygous for this mutation have a shiny, reflective, "polished" appearance




Genotype
MGI:3834211
ht2
Allelic
Composition		 Krt33aPlsh-3Btlr/Krt33a+
Genetic
Background		 C57BL/6J-Krt33aPlsh-3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt33aPlsh-3Btlr mutation (1 available); any Krt33a mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:145290 )
N
• mice with this mutation have a normal immune response to infection by Lysteria monocytogenes or by mouse cytomegalovirus (MCMV)
• peritoneal macrophages from mutant mice produce tumor necrosis factor alpha at levels similar to those of wild-type macrophages in response to stimulation by ligands for the seven toll-like receptors (TLRs) included in the TLR Signaling Screen: TLR1/2, TLR2/6, TLR3, TLR4, TLR7 and TLR9

integument
disheveled coat ( J:145290 )
• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"
greasy coat ( J:145290 )
• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"




Genotype
MGI:3805297
ht3
Allelic
Composition		 Krt33aPlsh/Krt33a+
Genetic
Background		 C57BL/6J-Krt33aPlsh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt33aPlsh mutation (0 available); any Krt33a mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
shiny fur ( J:137498 )
• the hair coats of mice heterozygous for this mutation have a shiny, reflective, "polished" appearance




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory