Phenotypes associated with this allele

• Allele Symbol: Dkk2^tm1Lmgd
• Allele Name: targeted mutation 1, Laboratory of Mammalian Genes and Development, Heiner Westphal
• Allele ID: MGI:3639316
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dkk2^tm1Lmgd/Dkk2^tm1Lmgd	involves: C57BL/6	MGI:3639887

Genotype
MGI:3639887

hm1

• Allelic Composition: Dkk2^tm1Lmgd/Dkk2^tm1Lmgd
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal cornea morphology ( J:109481 )

• mutant cornea is transformed into a stratified epidermis

abnormal ocular surface morphology ( J:109481 )

• hair growth is visible on the ocular surface of adults

• adults exhibit an opaque plaque on their ocular surface

abnormal cornea epithelium morphology ( J:109481 )

• sebaceous glands and conjunctiva-specific goblet cells are present in the epithelial layer of the cornea

cornea epithelium hyperplasia ( J:109481 )

• corneal epithelial hyperplasia is present in adults

growth/size/body

decreased body weight ( J:109481 )

• adult homozygotes are smaller in size than wild-type littermates due to a bone density defect