Phenotypes associated with this allele

• Allele Symbol: Itgb1^tm1.1Efu
• Allele Name: targeted mutation 1.1, Elaine Fuchs
• Allele ID: MGI:3639561
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itgb1^tm1.1Efu/Itgb1^tm1.1Efu	involves: 129X1/SvJ	MGI:3639578

Genotype
MGI:3639578

hm1

• Allelic Composition: Itgb1^tm1.1Efu/Itgb1^tm1.1Efu
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:108331 )

• at E6.5, homozygous embryos are resorbed, with only a residual population of trophoblast cells visible

embryo

absent inner cell mass ( J:108331 )

• at E6.5, embryos fail to develop an inner cell mass: embryos are identified by presence of persistent trophoblastic cells