Phenotypes associated with this allele

• Allele Symbol: Del(16Es2el-T10)2Bld
• Allele Name: deletion, Chr 16, Antonio Baldini 2
• Allele ID: MGI:3640125
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Del(16Es2el-T10)2Bld/+	B6.129S7-Del(16Es2el-T10)2Bld	MGI:5451006
ht2	Del(16Es2el-T10)2Bld/+	B6.Cg-Tyr^c-Brd Del(16Es2el-T10)2Bld	MGI:3713512
ht3	Del(16Es2el-T10)2Bld/+	involves: 129S7/SvEvBrd	MGI:3713484

Genotype
MGI:5451006

ht1

• Allelic Composition: Del(16Es2el-T10)2Bld/+
• Genetic Background: B6.129S7-Del(16Es2el-T10)2Bld

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:190908 )

N • despite changes in LTP, no defect in spatial memory are detected

nervous system

enhanced long-term potentiation ( J:190908 )

• in mature (16-20 weeks of age) but not in young (8-10 weeks of age) mice

• increased by about 100% compared to wild-type control littermates

• however, basal synaptic transmission is normal

Genotype
MGI:3713512

ht2

• Allelic Composition: Del(16Es2el-T10)2Bld/+
• Genetic Background: B6.Cg-Tyr^c-Brd Del(16Es2el-T10)2Bld

nervous system

nervous system phenotype ( J:110101 )

N • prepulse inhibition is normal

Genotype
MGI:3713484

ht3

• Allelic Composition: Del(16Es2el-T10)2Bld/+
• Genetic Background: involves: 129S7/SvEvBrd

cardiovascular system

cardiovascular system phenotype ( J:67409 )

N • no cardiovascular defects similar to those in other deletions are observed