Analysis Tools
mortality/aging
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• approximately 50% of mutant were dead within 2 days of birth
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reproductive system
growth/size/body
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• growth retardation with moderately larger fat pad mass in mutant mice at 15 weeks of age
|
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• smaller than wild-type at E18.5
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• when fed a high fat diet
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skeleton
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• found in embryos and postnatal dead mice
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rib fusion
(
J:77909
)
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• found in embryos and postnatal dead mice
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vision/eye
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• Background Sensitivity: seen only in BALB/cJ background but not in C57BL/6J background
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adipose tissue
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• when fed a high fat diet
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• increased in white fat pad mass when fed a high fat diet
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liver/biliary system
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• when fed a high fat diet
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• when fed a high fat diet
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homeostasis/metabolism
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• when fed a high fat diet
|
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• increased serum triglyceride and free fatty acid levels in the fed state when fed a high fat diet
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