All Phenotypes Vmn1r49<tm1Mom> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vmn1r49^tm1Mom
targeted mutation 1, Peter Mombaerts
MGI:3640467

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Adcy3^tm1Drs/Adcy3^tm1Drs Vmn1r49^tm1Mom/Vmn1r49⁺	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	MGI:3714864
cx2	Nrp2^tm1.2Mom/Nrp2^tm1.2Mom Vmn1r49^tm1Mom/Vmn1r49^tm1Mom	involves: 129P2/OlaHsd * C57BL/6J	MGI:3760744
cx3	Sema3f^tm1Mom/Sema3f^tm1Mom Vmn1r49^tm1Mom/Vmn1r49^tm1Mom	involves: 129P2/OlaHsd * C57BL/6J	MGI:3760745
cx4	Sema3f^tm1Mom/Sema3f⁺ Vmn1r49^tm1Mom/Vmn1r49^tm1Mom	involves: 129P2/OlaHsd * C57BL/6J	MGI:3760746

Allelic Composition	Adcy3^tm1Drs/Adcy3^tm1Drs Vmn1r49^tm1Mom/Vmn1r49⁺
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy3^tm1Drs mutation (0 available); any Adcy3 mutation (43 available)
Vmn1r49^tm1Mom mutation (1 available); any Vmn1r49 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:122528 )

N	• V1rb2+ olfactory sensory neuron targeting is normal

Allelic Composition	Nrp2^tm1.2Mom/Nrp2^tm1.2Mom Vmn1r49^tm1Mom/Vmn1r49^tm1Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrp2^tm1.2Mom mutation (1 available); any Nrp2 mutation (89 available)
Vmn1r49^tm1Mom mutation (1 available); any Vmn1r49 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:125485 )

• axonal projections exhibit defasciculation across the medial surface of the main olfactory bulb

Allelic Composition	Sema3f^tm1Mom/Sema3f^tm1Mom Vmn1r49^tm1Mom/Vmn1r49^tm1Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema3f^tm1Mom mutation (1 available); any Sema3f mutation (41 available)
Vmn1r49^tm1Mom mutation (1 available); any Vmn1r49 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal accessory olfactory bulb morphology ( J:125485 )

• Npr2+ axons erroneously project into the posterior accessory olfactory bulb

• V1rb2+ axons form glomeruli in the posterior accessory olfactory bulb unlike in wild-type mice

Allelic Composition	Sema3f^tm1Mom/Sema3f⁺ Vmn1r49^tm1Mom/Vmn1r49^tm1Mom
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal accessory olfactory bulb morphology ( J:125485 )

• in 18.2% of mice, exhibit misprojections of V1rb2+ axons in the accessory olfactory bulb

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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