cardiovascular system
• 18% to 60% of mice exhibit a common outflow tract unlike in wild-type mice
|
dextrocardia
(
J:145068
)
• in 5% of mice
|
mesocardia
(
J:145068
)
• in 36% of mice
|
digestive/alimentary system
• the tongue is fused to the lower jaw
|
• the stomach is right-sided in 32% of mice and centrally located in 18% of mice
|
• E13.5, the guts in some mice are reduced compared to in wild-type mice
|
vision/eye
• in 36% of mice
|
• some mice exhibit a diffuse pattern of pigment across the eye unlike in wild-type mice
|
craniofacial
• craniofacial defects are observed in 36% of mice
• at E13.5, mice exhibit narrow faces
|
micrognathia
(
J:145068
)
• the tongue is fused to the lower jaw
|
respiratory system
absent lungs
(
J:145068
)
• in 78% of mice
|
nervous system
exencephaly
(
J:145068
)
• in 91% of mice
|
embryo
• cilia are short and stumpy comapred to in wild-type mice
|
homeostasis/metabolism
limbs/digits/tail
polydactyly
(
J:145068
)
• in 100% of mice
|
pigmentation
• some mice exhibit a diffuse pattern of pigment across the eye unlike in wild-type mice
|
skeleton
micrognathia
(
J:145068
)
cellular
• cilia are short and stumpy comapred to in wild-type mice
|
growth/size/body
• the tongue is fused to the lower jaw
|