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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gucy1a2tm1.1Dko
targeted mutation 1.1, Doris Koesling
MGI:3640797
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gucy1a2tm1.1Dko/Gucy1a2tm1.1Dko involves: C57BL/6 MGI:3640806


Genotype
MGI:3640806
hm1
Allelic
Composition		 Gucy1a2tm1.1Dko/Gucy1a2tm1.1Dko
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gucy1a2tm1.1Dko mutation (0 available); any Gucy1a2 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:110362 )
N
• NO- and carbachol-induced relaxation of aortic rings and systolic blood pressure are similar to wild-type

hematopoietic system
hematopoietic system phenotype ( J:110362 )
N
• NO-induced inhibition of collagen-induced aggregation is similar to wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory