Phenotypes associated with this allele

• Allele Symbol: Kmt2a^tm1Djab
• Allele Name: targeted mutation 1, Malek Djabali
• Allele ID: MGI:3641250
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kmt2a^tm1Djab/Kmt2a^tm1Djab	involves: 129P2/OlaHsd * BALB/c	MGI:3653410

Genotype
MGI:3653410

hm1

• Allelic Composition: Kmt2a^tm1Djab/Kmt2a^tm1Djab
• Genetic Background: involves: 129P2/OlaHsd * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Skeletal abnormalities in Kmt2a^tm1Djab/Kmt2a^tm1Djab mice

skeleton

increased sternebra number ( J:109102 )

• an additional ossification center between sternebra 5 and the xiphoid process exhibiting seven sternebra instead of six

rib fusion ( J:109102 )

• uni- or bilateral fusions of ribs

abnormal arcus anterior morphology ( J:109102 )

• the anterior arch of the atlas was often missing or reduced in size

abnormal cervical axis morphology ( J:109102 )

• the axis resembles the atlas

cervical vertebral transformation ( J:109102 )

• displayed a typical posterior transformation of C6 and C7 revealed by the presence of rudimentary ribs

• the axis resembles the atlas