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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(CD2-Sh2d1a)#Vei
transgene insertion, Andre Veillette
MGI:3641449
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(CD2-Sh2d1a)#Vei/0 involves: 129S1/Sv * 129X1/SvJ MGI:3641450


Genotype
MGI:3641450
tg1
Allelic
Composition		 Tg(CD2-Sh2d1a)#Vei/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased natural killer cell mediated cytotoxicity ( J:110195 )
• overexpression considerably enhances the capacity to kill CD48+ C4.4-25 target cells in vitro; a moderate increase in the killing of other CD48+ targets is also observed

hematopoietic system
increased natural killer cell mediated cytotoxicity ( J:110195 )
• overexpression considerably enhances the capacity to kill CD48+ C4.4-25 target cells in vitro; a moderate increase in the killing of other CD48+ targets is also observed




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory