About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il3ram1
mutation 1
MGI:3652833
Summary 10 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Il3ram1/Il3ram1 A/HeJ MGI:3837357
hm2
 		Il3ram1/Il3ram1 A/J MGI:3653035
hm3
 		Il3ram1/Il3ram1 AKR/J MGI:3837353
hm4
 		Il3ram1/Il3ram1 A/WySnJ MGI:3837356
hm5
 		Il3ram1/Il3ram1 BUB/BnJ MGI:3837358
hm6
 		Il3ram1/Il3ram1 C58/J MGI:3837352
hm7
 		Il3ram1/Il3ram1 CE/J MGI:3837360
hm8
 		Il3ram1/Il3ram1 NZB/BlNJ MGI:3837355
hm9
 		Il3ram1/Il3ram1 RF/J MGI:3837354
hm10
 		Il3ram1/Il3ram1 SM/J MGI:3837359


Genotype
MGI:3837357
hm1
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3653035
hm2
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3, but normal colony growth occurs in response to GM-CSF
abnormal leukopoiesis ( J:23971 )
• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone

immune system
abnormal leukopoiesis ( J:23971 )
• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone




Genotype
MGI:3837353
hm3
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 AKR/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837356
hm4
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/WySnJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837358
hm5
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 BUB/BnJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837352
hm6
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 C58/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837360
hm7
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 CE/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837355
hm8
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 NZB/BlNJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837354
hm9
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 RF/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837359
hm10
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 SM/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory