About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Foxn1tm2Tbo
targeted mutation 2, Thomas Boehm
MGI:3653425
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Foxn1tm2Tbo/Foxn1tm2Tbo involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3653833
cn2
 		Foxn1tm2Tbo/Foxn1tm2Tbo
Tg(KRT14-cre/ERT2)1Ipc/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3653834


Genotype
MGI:3653833
hm1
Allelic
Composition		 Foxn1tm2Tbo/Foxn1tm2Tbo
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1tm2Tbo mutation (0 available); any Foxn1 mutation (106 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
hairless ( J:110046 )
• homozygotes lack a normal hair coat similar to nude (nu/nu) mice




Genotype
MGI:3653834
cn2
Allelic
Composition		 Foxn1tm2Tbo/Foxn1tm2Tbo
Tg(KRT14-cre/ERT2)1Ipc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1tm2Tbo mutation (0 available); any Foxn1 mutation (106 available)
Tg(KRT14-cre/ERT2)1Ipc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased T cell number ( J:110046 )
• mutants have higher proportions of activated peripheral T cells (CD44high CD62Llow CD25high) than wild-type

immune system
increased T cell number ( J:110046 )
• mutants have higher proportions of activated peripheral T cells (CD44high CD62Llow CD25high) than wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory