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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(tetO-Aurkb,lacZ)41Kra
transgene insertion 41, Katya Ravid
MGI:3656025
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(PF4-tTA/VP16)42Kra/0
Tg(tetO-Aurkb,lacZ)41Kra/0
FVB/NJ-Tg(tetO-Aurkb,lacZ)41Kra Tg(PF4-tTA/VP16)42Kra MGI:3656381


Genotype
MGI:3656381
cx1
Allelic
Composition
Tg(PF4-tTA/VP16)42Kra/0
Tg(tetO-Aurkb,lacZ)41Kra/0
Genetic
Background
FVB/NJ-Tg(tetO-Aurkb,lacZ)41Kra Tg(PF4-tTA/VP16)42Kra
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PF4-tTA/VP16)42Kra mutation (1 available)
Tg(tetO-Aurkb,lacZ)41Kra mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• after LPS treatment, mice show accumulation of platelets in the liver and lungs in the induced (doxycycline removed) state

hematopoietic system
• induced mice show no increase in platelet number compared to control
• after LPS treatment, mice show accumulation of platelets in the liver and lungs in the induced (doxycycline removed) state

immune system
• induced mice show no increase in platelet number compared to control





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory