About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(tetO-Aurkb,lacZ)41Kra
transgene insertion 41, Katya Ravid
MGI:3656025
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(PF4-tTA/VP16)42Kra/0
Tg(tetO-Aurkb,lacZ)41Kra/0 		FVB/NJ-Tg(tetO-Aurkb,lacZ)41Kra Tg(PF4-tTA/VP16)42Kra MGI:3656381


Genotype
MGI:3656381
cx1
Allelic
Composition		 Tg(PF4-tTA/VP16)42Kra/0
Tg(tetO-Aurkb,lacZ)41Kra/0
Genetic
Background		 FVB/NJ-Tg(tetO-Aurkb,lacZ)41Kra Tg(PF4-tTA/VP16)42Kra
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PF4-tTA/VP16)42Kra mutation (1 available)
Tg(tetO-Aurkb,lacZ)41Kra mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal platelet physiology ( J:104239 )
• after LPS treatment, mice show accumulation of platelets in the liver and lungs in the induced (doxycycline removed) state

hematopoietic system
abnormal thrombopoiesis ( J:104239 )
• induced mice show no increase in platelet number compared to control
abnormal platelet physiology ( J:104239 )
• after LPS treatment, mice show accumulation of platelets in the liver and lungs in the induced (doxycycline removed) state

immune system
abnormal thrombopoiesis ( J:104239 )
• induced mice show no increase in platelet number compared to control




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory