Phenotypes associated with this allele

• Allele Symbol: Gnptab⁺
• Allele Name: wild type
• Allele ID: MGI:3658412
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gnptab^em1(IMPC)Mbp/Gnptab^+	C57BL/6N-Gnptab^em1(IMPC)Mbp/MbpMmucd	MGI:6461301
ht2	Gnptab^nym/Gnptab^+	involves: BALB/cAnNHsd * C3H/HeNHsd	MGI:5790647

Genotype
MGI:6461301

ht1

• Allelic Composition: Gnptab^em1(IMPC)Mbp/Gnptab⁺
• Genetic Background: C57BL/6N-Gnptab^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Gnptab

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - UCD

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

♂

IMPC - UCD

abnormal heart morphology ( J:211773 )

IMPC - UCD

enlarged heart ( J:211773 )

IMPC - UCD

small heart ( J:211773 )

♀

IMPC - UCD

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

♀

IMPC - UCD

small stomach ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - UCD

enlarged kidney ( J:211773 )

♂

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - UCD

enlarged ovary ( J:211773 )

♀

IMPC - UCD

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

cataract ( J:211773 )

♂

IMPC - UCD

abnormal vitreous body morphology ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:5790647

ht2

• Allelic Composition: Gnptab^nym/Gnptab⁺
• Genetic Background: involves: BALB/cAnNHsd * C3H/HeNHsd

normal phenotype

no abnormal phenotype detected ( J:218156 )

• despite a 1.7-fold increase in beta-hexosaminidase and a 2.4-fold increase in alpha-mannosidase, heterozygotes appear overtly normal with no apparent changes in fertility, size, body weight progression, facial features, survival, motor coordination, and muscle strength