Phenotypes associated with this allele

• Allele Symbol: Glra2^tm1Clc
• Allele Name: targeted mutation 1, Constance L Cepko
• Allele ID: MGI:3662671
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Glra2^tm1Clc/Glra2^tm1Clc	involves: 129X1/SvJ	MGI:3662883

Genotype
MGI:3662883

hm1

• Allelic Composition: Glra2^tm1Clc/Glra2^tm1Clc
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal single cell response ( J:111414 )

♀ • E17 cortical pyramidal neurons fail to respond to glycine or taurine in single cell patch clamp assays

♀ • however, these cells respond normally to GABA and cortex morphology at P0 and in adults is indistinguishable from wild-type

vision/eye

vision/eye phenotype ( J:111414 )

♀N • retinal morphology is similar to wild-type and no differences in electroreinograms are detected

reproductive system

reproductive system phenotype ( J:111414 )

♀N • fertile with normal breeding behavior

behavior/neurological

behavior/neurological phenotype ( J:111414 )

♀N • normal gait and feeding behavior