mortality/aging
• most mice die prior to weaning of unknown causes
|
growth/size/body
heterotaxia
(
J:168691
)
• in 39% of mice at E11.5 to E15.5
|
• in 19% of mice at E11.5 to E15.5
|
• in some mice
|
• in some mice
|
• in 8% of mice at E11.5 to E15.5
|
embryo
• cilia are short compared to in wild-type mice
|
nervous system
hydrocephaly
(
J:168691
)
renal/urinary system
N |
• mice do not develop kidney cysts
|
respiratory system
• in some mice
|
• in some mice
|
cellular
• cilia are short compared to in wild-type mice
|