Phenotypes associated with this allele

• Allele Symbol: Ncam2^tm1Mom
• Allele Name: targeted mutation 1, Peter Mombaerts
• Allele ID: MGI:3663377
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ncam2^tm1Mom/Ncam2^tm1Mom	involves: 129P2/OlaHsd * C57BL/6	MGI:3663449

Genotype
MGI:3663449

hm1

• Allelic Composition: Ncam2^tm1Mom/Ncam2^tm1Mom
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:111928 )

• glomeruli in mutants differ from wild-type; there is a notable absence of defined dendritic compartments like wild-type

• axons and dendrites appear homogeneously interdigitated and the dendrites are not bundled as in wild-type; there is an apparent increase in numbers of myelinated dendrites

taste/olfaction

abnormal olfactory system physiology ( J:111928 )

• mutants have greater olfactory acuity compared to wild-type littermates from heterozygous matings; untrained mice find a buried cookie in the cage faster than wild-type littermates

• after 4 days of training, mutants and wild-type are indistinguishable