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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Pcp2-cre)3Mdk
transgene insertion 3, Michael D Koob
MGI:3664534
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Klhl1/Atxn8ostm1Mdk/Klhl1/Atxn8ostm1Mdk
Tg(Pcp2-cre)3Mdk/0
involves: 129S1/Sv * C57BL/6 * FVB/N * SJL MGI:3689862
cn2
BY367451tm1Mdk/BY367451tm1Mdk
Tg(Pcp2-cre)3Mdk/0
involves: 129S1/Sv * C57BL/6 * FVB/N * SJL MGI:3689863


Genotype
MGI:3689862
cn1
Allelic
Composition
Klhl1/Atxn8ostm1Mdk/Klhl1/Atxn8ostm1Mdk
Tg(Pcp2-cre)3Mdk/0
Genetic
Background
involves: 129S1/Sv * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl1/Atxn8ostm1Mdk mutation (0 available); any Klhl1 mutation (52 available)
Tg(Pcp2-cre)3Mdk mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• loss of motor coordination at 24 weeks of age in a rotarod test

nervous system
• layer normal at 6 weeks but definitely thinner at 24 weeks of age
• dendritic atrophy of Purkinje cells seen but Purkinje cells themselves display an overall normal morphology




Genotype
MGI:3689863
cn2
Allelic
Composition
BY367451tm1Mdk/BY367451tm1Mdk
Tg(Pcp2-cre)3Mdk/0
Genetic
Background
involves: 129S1/Sv * C57BL/6 * FVB/N * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• loss of motor coordination at 24 weeks of age in a rotarod test

nervous system
• layer normal at 6 weeks but definitely thinner at 24 weeks of age
• dendritic atrophy of Purkinje cells seen but Purkinje cells themselves display an overall normal morphology





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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory