Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(Pcp2-cre)3Mdk transgene insertion 3, Michael D Koob MGI:3664534 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• loss of motor coordination at 24 weeks of age in a rotarod test
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• layer normal at 6 weeks but definitely thinner at 24 weeks of age
• dendritic atrophy of Purkinje cells seen but Purkinje cells themselves display an overall normal morphology
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• loss of motor coordination at 24 weeks of age in a rotarod test
|
|
• layer normal at 6 weeks but definitely thinner at 24 weeks of age
• dendritic atrophy of Purkinje cells seen but Purkinje cells themselves display an overall normal morphology
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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