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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfand2aGt(XM071)Byg
gene trap XM071, BayGenomics
MGI:3664591
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfand2aGt(XM071)Byg/Zfand2aGt(XM071)Byg involves: 129P2/OlaHsd MGI:3703716


Genotype
MGI:3703716
hm1
Allelic
Composition		 Zfand2aGt(XM071)Byg/Zfand2aGt(XM071)Byg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfand2aGt(XM071)Byg mutation (0 available); any Zfand2a mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:112707 )
• mutant cells accumulate more ubiquinated proteins when exposed to arsenite; as well, cells show higher levels of stress upon arsenite exposure compared to wild-type
• cells null for Zfand2a display impaired substrate degradation after arsenite treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory