Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tcra-Jtm1Kgwa targeted mutation 1, Osami Kanagawa MGI:3665411 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• majority of CD3+ double negative (DN) cells express the transgenic TCR alpha, but only 3-5% of double- and single-positive cells express it
|
|
• majority of CD3+ double negative (DN) cells express the transgenic TCR alpha, but only 3-5% of double- and single-positive cells express it
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• an increase in number from 5 to 50% in transgenic Tcra-expressing cells is observed in single positive cells; deletion of the transgenic TCR by secondary rearrangement is reduced significantly
|
|
• an increase from 3 to 30% in transgenic Tcra-expressing cells is observed in double-positive cells; deletion of the transgenic TCR by secondary rearrangement is reduced significantly
|
|
• an increase in number from 5 to 50% in transgenic Tcra-expressing cells is observed in single positive cells; deletion of the transgenic TCR by secondary rearrangement is reduced significantly
|
|
• an increase from 3 to 30% in transgenic Tcra-expressing cells is observed in double-positive cells; deletion of the transgenic TCR by secondary rearrangement is reduced significantly
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/19/2024 MGI 6.24 |
|
|
|
||
