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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhohtm1Daw
targeted mutation 1, David A Williams
MGI:3687310
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rhohtm1Daw/Rhohtm1Daw involves: 129 * C57BL/6 MGI:3690086


Genotype
MGI:3690086
hm1
Allelic
Composition		 Rhohtm1Daw/Rhohtm1Daw
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhohtm1Daw mutation (0 available); any Rhoh mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
thymus hypoplasia ( J:113565 )
• mutant thymuses were much smaller than wild-type
• thymic cellularity was 30% that of wild-type
decreased T cell number ( J:113565 )
• T cell lymphopenia of the peripheral blood, spleen and lymph node

immune system
thymus hypoplasia ( J:113565 )
• mutant thymuses were much smaller than wild-type
• thymic cellularity was 30% that of wild-type
decreased T cell number ( J:113565 )
• T cell lymphopenia of the peripheral blood, spleen and lymph node

endocrine/exocrine glands
thymus hypoplasia ( J:113565 )
• mutant thymuses were much smaller than wild-type
• thymic cellularity was 30% that of wild-type




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory