Phenotypes associated with this allele

• Allele Symbol: Trp53^tm3Xu
• Allele Name: targeted mutation 3, Yang Xu
• Allele ID: MGI:3687352
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trp53^tm3Xu/Trp53^tm3Xu	Not Specified	MGI:3689811

Genotype
MGI:3689811

hm1

• Allelic Composition: Trp53^tm3Xu/Trp53^tm3Xu
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:112302 )

N • no apparent difference in the life span between the wild-type and mutant mice

cellular

increased cellular sensitivity to ionizing radiation ( J:112302 )

• increased apoptosis after ionizing radiation among thymocytes isolated from 4- to 6-week-old mice

• increased apoptosis after ionizing radiation among epithelium cells from the small intestine in 2-month-old mice

• increased apoptosis after ionizing radiation among retinal cells in 3 days old mice