pigmentation
• mice have black coats with regions of hypopigmentation ranging in size from a few hairs to small patches
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• by transmission electron microscopy, patches of hypopigmentation in the retinal pigment epithelium are apparent
• pigmentation of the choroid appears normal
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• melanosomes in the retinal pigment epithelium are irregularly shaped and incompletely melanized; melanosomes elsewhere are smaller than normal
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vision/eye
• by transmission electron microscopy, patches of hypopigmentation in the retinal pigment epithelium are apparent
• pigmentation of the choroid appears normal
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integument
• mice have black coats with regions of hypopigmentation ranging in size from a few hairs to small patches
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