Phenotypes associated with this allele

• Allele Symbol: Cyfip1^l7Rl1-3R
• Allele Name: 3 Oak Ridge
• Allele ID: MGI:3689299
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cyfip1^l7Rl1-3R/Cyfip1^l7Rl1-3R	Mixed stock	MGI:3689300

Genotype
MGI:3689300

hm1

• Allelic Composition: Cyfip1^l7Rl1-3R/Cyfip1^l7Rl1-3R
• Genetic Background: Mixed stock

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between somite formation and embryo turning, complete penetrance ( J:163586 )

• embryonic development arrest occurs at around 8.5dpc

prenatal lethality, complete penetrance ( J:100221 )

• animals die prenatally

embryo

abnormal rostral-caudal body axis extension ( J:163586 )

• the anterior posterior axis of the mutant embryos was not able to further elongate after 7.5-8.5dpc

open neural tube ( J:163586 )

• neural tube closure was not observed in mutant embryos by 9.5dpc

kinked neural tube ( J:163586 )

delayed somite formation ( J:163586 )

• mutant embryos had only 6-12 somties at 9.5dpc, which is the somite number for the normal embryos at 8.5dpc

impaired somite development ( J:163586 )

• although the somite structures were visible, they appeared disorganized

nervous system

open neural tube ( J:163586 )

• neural tube closure was not observed in mutant embryos by 9.5dpc

kinked neural tube ( J:163586 )