Analysis Tools|
Allele Symbol Allele Name Allele ID |
Il5tm3Anjm targeted mutation 3, Andrew NJ McKenzie MGI:3689810 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• upon infection with Schistosoma mansoni eggs, primary granuloma formation and volume is equivalent to wild-type
• volumes of secondary granulomas after second exposure with parasite eggs are reduced compared to wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• upon infection with Schistosoma mansoni eggs, primary granuloma formation and volume is equivalent to wild-type
• volumes of secondary granulomas after second exposure to parasite eggs are reduced by ~50% compared to wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• primary granuloma formation and volumes after infection are reduced ~4-fold compared to wild-type
• volumes of secondary granulomas after second exposure with parasite eggs are reduced compared to wild-type
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• primary granuloma formation and volumes after infection are reduced ~4-fold compared to wild-type
• volumes of secondary granulomas after second exposure with parasite eggs are reduced compared to wild-type
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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