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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptpn11tm1Yan
targeted mutation 1, Wentian Yang
MGI:3690333
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ptpn11tm1Yan/Ptpn11tm1Yan
Tg(Ckmm-cre)5Khn/0 		involves: 129/Sv * C57BL/6 * FVB MGI:3697622


Genotype
MGI:3697622
cn1
Allelic
Composition		 Ptpn11tm1Yan/Ptpn11tm1Yan
Tg(Ckmm-cre)5Khn/0
Genetic
Background		 involves: 129/Sv * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn11tm1Yan mutation (1 available); any Ptpn11 mutation (46 available)
Tg(Ckmm-cre)5Khn mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
decreased skeletal muscle fiber size ( J:114499 )
• exhibit a decrease in skeletal myofiber size concomitant with a reduction in larger myofibers as well as a decrease in myonuclear number
decreased skeletal muscle fiber number ( J:114499 )
• exhibit a decrease in the number of skeletal muscle fibers, more specifically a reduction in type I slow muscle fibers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory