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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(APOE-PCSK9)1Jdh
transgene insertion 1, Jay D Horton
MGI:3691618
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(APOE-PCSK9)1Jdh/0 Not Specified MGI:3691619


Genotype
MGI:3691619
tg1
Allelic
Composition
Tg(APOE-PCSK9)1Jdh/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice have a marked increase in plasma LDL cholesterol similar to Ldlr-null male mice
• in wild-type mice parabiosed with Ldlr-null mice (resulting in shared circulation), plasma total cholesterol levels did not increase significantly over pre-surgery levels





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory