Phenotypes associated with this allele

• Allele Symbol: Del(6)1Mom
• Allele Name: deletion, Chr 6, Peter Mombaerts
• Allele ID: MGI:3691951
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(6)1Mom/Del(6)1Mom	involves: 129S6/SvEvTac * 129S7/SvEvBrd	MGI:3691952

Genotype
MGI:3691952

hm1

• Allelic Composition: Del(6)1Mom/Del(6)1Mom
• Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:78894 )

N • normal motor activity, open-field locomotor activity, and depression-related behaviors

decreased aggression ( J:78894 )

• although male aggression is normal and maternal pup retrieval is normal, lactating females show diminished maternal aggression towards intruders in the form of latency to first attack, total time of attack, number of attacks, number of fights, and number of tail rattles

abnormal maternal behavior ( J:78894 )

♀ • lactating females are less aggressive toward intruders

decreased mounting behavior ( J:78894 )

♂ • males have decreased sexual drive as evidenced by a lower percentage of males who mounted females, although plasma testosterone levels after oxposure to female mice is normal

abnormal mating preference ( J:78894 )

♂ • socially inexperienced homozygous males have a decreased propensity to mount other males

reproductive system

reproductive system phenotype ( J:78894 )

N • normal fertility, body weight thoughtout development, and oestrous cycling

taste/olfaction

taste/olfaction phenotype ( J:78894 )

N • no statistically significant difference is found in the latency to find the cookie test

nervous system

avnosmia ( J:78894 )

• deletion of this vomeronasal 1 receptor cluster leaves homozygotes non-responsive to 3 of 8 compounds tested