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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Myh6-Tnnt2*R92Q)1Lnwd
transgene insertion 1, Leslie A Leinwand
MGI:3692448
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Myh6-Tnnt2*R92Q)1Lnwd/0 involves: C57BL/6 MGI:5755251


Genotype
MGI:5755251
tg1
Allelic
Composition		 Tg(Myh6-Tnnt2*R92Q)1Lnwd/0
Genetic
Background		 involves: C57BL/6
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart atrium morphology ( J:56911 )
• progressive atrial hypertrophy
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers
abnormal heart ventricle morphology ( J:56911 )
• ventricular mass decreases by about 18%

muscle
abnormal sarcomere morphology ( J:56911 )
• sarcomere lengths are shorter in left ventricular myocytes

growth/size/body
cardiac hypertrophy ( J:56911 )
• progressive atrial hypertrophy
• hearts exhibit expression of hypertrophic markers




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory