Phenotypes associated with this allele

• Allele Symbol: Myoc^tm2.1Rjo
• Allele Name: targeted mutation 2.1, Randy Johnson
• Allele ID: MGI:3693012
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myoc^tm2.1Rjo/Myoc^tm2.1Rjo	either: (involves: 129S7/SvEvBrd * AKR/J * C57BL/6J) or (involves: 129S7/SvEvBrd * BALB/c * C57BL/6J)	MGI:3696395
hm2	Myoc^tm2.1Rjo/Myoc^tm2.1Rjo	involves: 129S7/SvEvBrd * C57BL/6J	MGI:3696392
hm3	Myoc^tm2.1Rjo/Myoc^tm2.1Rjo	involves: 129S7/SvEvBrd * C57BL/6J * CBA/CaJ	MGI:3696393

Genotype
MGI:3696395

hm1

• Allelic Composition: Myoc^tm2.1Rjo/Myoc^tm2.1Rjo
• Genetic Background: either: (involves: 129S7/SvEvBrd * AKR/J * C57BL/6J) or (involves: 129S7/SvEvBrd * BALB/c * C57BL/6J)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:115971 )

N • Background Sensitivity: no indication of changes in intraocular pressure, unlike mice on a predominantly C57BL/6 background where pressure is reduced

Genotype
MGI:3696392

hm2

• Allelic Composition: Myoc^tm2.1Rjo/Myoc^tm2.1Rjo
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

vision/eye

vision/eye phenotype ( J:115971 )

N • no indication of changes in iridocorneal angles and no glaucoma-related changes in eye morphology

abnormal intraocular pressure ( J:115971 )

• Background Sensitivity: slight but significant reduction in intraocular pressure at 9 and 12 months of age, unlike mice where the background includes AKR/J, BALB/c, or CBA/CaJ

Genotype
MGI:3696393

hm3

• Allelic Composition: Myoc^tm2.1Rjo/Myoc^tm2.1Rjo
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * CBA/CaJ

vision/eye

vision/eye phenotype ( J:115971 )

N • Background Sensitivity: no indication of changes in intraocular pressure, unlike mice on a predominantly C57BL/6 background where pressure is reduced

N • no glaucoma related changes in eye morphology