All Phenotypes Sall4<tm2.1Tre> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sall4^tm2.1Tre
targeted mutation 2.1, Mathias Treier
MGI:3693080

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sall4^tm2.1Tre/Sall4^tm2.1Tre	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	MGI:3693089
ht2	Sall4^tm1Tre/Sall4^tm2.1Tre	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	MGI:3693084
cn3	Sall4^tm2Tre/Sall4^tm2.1Tre Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * CD-1	MGI:3693081

Allelic Composition	Sall4^tm2.1Tre/Sall4^tm2.1Tre
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sall4^tm2.1Tre mutation (0 available); any Sall4 mutation (144 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:115635 )

• no prestreak embryos are found; empty implantations are regularly observed

Allelic Composition	Sall4^tm1Tre/Sall4^tm2.1Tre
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sall4^tm1Tre mutation (0 available); any Sall4 mutation (144 available)
Sall4^tm2.1Tre mutation (0 available); any Sall4 mutation (144 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:115635 )

• no prestreak embryos are found; empty implantations are regularly observed

Allelic Composition	Sall4^tm2Tre/Sall4^tm2.1Tre Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3^{Tg(Sox2-cre)1Amc} mutation (5 available); any Edil3 mutation (42 available)
Sall4^tm2.1Tre mutation (0 available); any Sall4 mutation (144 available)
Sall4^tm2Tre mutation (0 available); any Sall4 mutation (144 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:115635 )

embryo

embryonic growth arrest ( J:115635 )

• embryo development is arrested at the late primitive streak stage, before somite development

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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