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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Or10a5tm1Mom
targeted mutation 1, Peter Mombaerts
MGI:3693374
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Or10a5tm1Mom/Or10a5tm1Mom involves: 129P2/OlaHsd * C57BL/6 MGI:3694218
cx2
 		Or10a4tm6(Or10a5)Mom/Or10a4+
Or10a5tm1Mom/Or10a5+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:3694213


Genotype
MGI:3694218
hm1
Allelic
Composition		 Or10a5tm1Mom/Or10a5tm1Mom
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or10a5tm1Mom mutation (1 available); any Or10a5 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory neuron innervation pattern ( J:90716 )
• axons coalesce into separate glomeruli




Genotype
MGI:3694213
cx2
Allelic
Composition		 Or10a4tm6(Or10a5)Mom/Or10a4+
Or10a5tm1Mom/Or10a5+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or10a4tm6(Or10a5)Mom mutation (1 available); any Or10a4 mutation (22 available)
Or10a5tm1Mom mutation (1 available); any Or10a5 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory bulb morphology ( J:90716 )
• novel glomeruli form ventrally to endogenous P3 glomeruli, and are separated by 2-3 glomeruli; shift is not as greater as P4-P2 glomeruli shift relative toP4 glomeruli
abnormal olfactory neuron innervation pattern ( J:90716 )
• mutant axons do not reroute to P3 glomeruli




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory