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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adcy7tm1Btab
targeted mutation 1, Boris Tabakoff
MGI:3693867
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adcy7tm1Btab/Adcy7tm1Btab B6.129S7-Adcy7tm1Btab MGI:3695043
ht2
 		Adcy7tm1Btab/Adcy7+ B6.129S7-Adcy7tm1Btab MGI:3695044


Genotype
MGI:3695043
hm1
Allelic
Composition		 Adcy7tm1Btab/Adcy7tm1Btab
Genetic
Background		 B6.129S7-Adcy7tm1Btab
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy7tm1Btab mutation (0 available); any Adcy7 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:116184 )
• partial lethality before birth, no data on specific time of death provided




Genotype
MGI:3695044
ht2
Allelic
Composition		 Adcy7tm1Btab/Adcy7+
Genetic
Background		 B6.129S7-Adcy7tm1Btab
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adcy7tm1Btab mutation (0 available); any Adcy7 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal depression-related behavior ( J:116184 )
• females, but not males, display reduced immobility in the forced swim test, but not in the tail suspension test
• however, no difference in anxiety related behaviors is seen compared to wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory