About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt71Mhdarco13
Martin Hrabe de Angelis reduced coat 13
MGI:3693874
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Krt71Mhdarco13/Krt71Mhdarco13 C3HeB/FeJ-Krt71Mhdarco13 MGI:3695041
ht2
 		Krt71Mhdarco13/Krt71+ C3HeB/FeJ-Krt71Mhdarco13 MGI:3695042


Genotype
MGI:3695041
hm1
Allelic
Composition		 Krt71Mhdarco13/Krt71Mhdarco13
Genetic
Background		 C3HeB/FeJ-Krt71Mhdarco13
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt71Mhdarco13 mutation (1 available); any Krt71 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Phenotype of Krt71Mhdarco12/+ or Krt71Mhdarco12/Krt71Mhdarco12 and Krt71Mhdarco13/+ or Krt71Mhdarco13/Krt71Mhdarco13 mice.

integument
waved hair ( J:116206 )
• curl visible by P10
• becomes less pronounced by 3 months of age
abnormal hair follicle inner root sheath morphology ( J:116206 )
• irregular formation of Henle's and Huxley's layers
• areas of increased thickness in Henle's layer are associated with round structures
• intermediate keratin filaments in Henle's layer form large whorls with only very short linear filamentous structures




Genotype
MGI:3695042
ht2
Allelic
Composition		 Krt71Mhdarco13/Krt71+
Genetic
Background		 C3HeB/FeJ-Krt71Mhdarco13
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt71Mhdarco13 mutation (1 available); any Krt71 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Phenotype of Krt71Mhdarco12/+ or Krt71Mhdarco12/Krt71Mhdarco12 and Krt71Mhdarco13/+ or Krt71Mhdarco13/Krt71Mhdarco13 mice.

integument
waved hair ( J:116206 )
• curl visible by P10
• becomes less pronounced by 3 months of age
abnormal hair follicle inner root sheath morphology ( J:116206 )
• irregular formation of Henle's and Huxley's layers
• areas of increased thickness in Henle's layer are associated with round structures
• intermediate keratin filaments in Henle's layer form large whorls with short lengths of linear intermediate filament bundles




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory