Phenotypes associated with this allele

• Allele Symbol: Arc^tm1Stl
• Allele Name: targeted mutation 1, Susumu Tonegawa
• Allele ID: MGI:3694120
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arc^tm1Stl/Arc^tm1Stl	involves: C57BL/6	MGI:3694763

Genotype
MGI:3694763

hm1

• Allelic Composition: Arc^tm1Stl/Arc^tm1Stl
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal nervous system physiology ( J:115255 )

• in visual cortex, homozygotes show increased number of neurons with low orientation specificity when stimulated by horizontal or vertical stripes; cells responding to both orientations are more frequent than in heterozygotes

abnormal nervous system electrophysiology ( J:115255 )

• there is reduced orientation selectivity of neuronal spiking response compared to wild-type or heterozygous mice