Phenotypes associated with this allele

• Allele Symbol: Tg(Amelx-Dspp)13Mlp
• Allele Name: transgene insertion 13, Michael L Paine
• Allele ID: MGI:3695684
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Amelx-Dspp)13Mlp/Tg(Amelx-Dspp)13Mlp	involves: C57BL/6J * CBA/J * DBA/2J	MGI:4821772

Genotype
MGI:4821772

tg1

• Allelic Composition: Tg(Amelx-Dspp)13Mlp/Tg(Amelx-Dspp)13Mlp
• Genetic Background: involves: C57BL/6J * CBA/J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal enamel morphology ( J:101218 , J:120871 )

• mice exhibit enamel of varying thickness (J:101218)

• enamel dysmorphology covers large regions where no prismatic structure is evident (J:101218)

• fracture toughness of dentinoenamel junction (DEJ) is 2 fold weaker than wildtype (J:120871)

• enamel hardness and toughness is significantly decreased as compared to wild-type (J:120871)

abnormal enamel rod pattern ( J:101218 , J:120871 )

• rods are not evident (J:101218)

• individual crystallites rarely run in parallel to neighboring crystallites (J:101218)

• microscopy reveals large areas where rods are not clearly defined (J:120871)

• severely effected areas exhibit an amorphous appearance (J:120871)

• decussation patterns are not clearly defined (J:120871)

enamel pits ( J:101218 )

• enamel surface is pitted

reduced enamel thickness ( J:120871 )

• enamel is thin and of an irregular form

skeleton

abnormal enamel morphology ( J:101218 , J:120871 )

• mice exhibit enamel of varying thickness (J:101218)

• enamel dysmorphology covers large regions where no prismatic structure is evident (J:101218)

• fracture toughness of dentinoenamel junction (DEJ) is 2 fold weaker than wildtype (J:120871)

• enamel hardness and toughness is significantly decreased as compared to wild-type (J:120871)

abnormal enamel rod pattern ( J:101218 , J:120871 )

• rods are not evident (J:101218)

• individual crystallites rarely run in parallel to neighboring crystallites (J:101218)

• microscopy reveals large areas where rods are not clearly defined (J:120871)

• severely effected areas exhibit an amorphous appearance (J:120871)

• decussation patterns are not clearly defined (J:120871)

enamel pits ( J:101218 )

• enamel surface is pitted

reduced enamel thickness ( J:120871 )

• enamel is thin and of an irregular form

growth/size/body

abnormal enamel morphology ( J:101218 , J:120871 )

• mice exhibit enamel of varying thickness (J:101218)

• enamel dysmorphology covers large regions where no prismatic structure is evident (J:101218)

• fracture toughness of dentinoenamel junction (DEJ) is 2 fold weaker than wildtype (J:120871)

• enamel hardness and toughness is significantly decreased as compared to wild-type (J:120871)

abnormal enamel rod pattern ( J:101218 , J:120871 )

• rods are not evident (J:101218)

• individual crystallites rarely run in parallel to neighboring crystallites (J:101218)

• microscopy reveals large areas where rods are not clearly defined (J:120871)

• severely effected areas exhibit an amorphous appearance (J:120871)

• decussation patterns are not clearly defined (J:120871)

enamel pits ( J:101218 )

• enamel surface is pitted

reduced enamel thickness ( J:120871 )

• enamel is thin and of an irregular form