mortality/aging
• present at E11.5 but none are born alive
• growth arrest around E10.5
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embryo
• arrest around E10.5
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• visible starting around E10.5
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• reduced thickness at E11.5
• at E9.5 the branched morphology is absent and the chorioallantoic interface remains flat until E11.5
• however, spongiotrophoblast and trophoblast giant cells appear normal
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• fetal vessels do not lie adjacent to the maternal blood sinus
• fetal vessels fail to penetrate the labyrinth layer
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growth/size/body
• visible starting around E10.5
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cardiovascular system
• fetal vessels do not lie adjacent to the maternal blood sinus
• fetal vessels fail to penetrate the labyrinth layer
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