About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Nlrp1b)1Die
transgene insertion 1, William Dietrich
MGI:3695919
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Nlrp1b)1Die/0 involves: 129S1/SvImJ * C57BL/6 * SJL MGI:3696110


Genotype
MGI:3696110
tg1
Allelic
Composition		 Tg(Nlrp1b)1Die/0
Genetic
Background		 involves: 129S1/SvImJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nlrp1b)1Die mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal macrophage physiology ( J:99748 )
• transgenic bone marrow-derived macrophages are fully susceptible to necrosis induction by lethal toxin (LeTx) derived from B. anthracis, whereas macrophages from non-transgenic littermates are resistant

hematopoietic system
abnormal macrophage physiology ( J:99748 )
• transgenic bone marrow-derived macrophages are fully susceptible to necrosis induction by lethal toxin (LeTx) derived from B. anthracis, whereas macrophages from non-transgenic littermates are resistant




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory