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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map3k7tm1.1Mds
targeted mutation 1.1, Michael D Schneider
MGI:3696053
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Map3k7tm1.1Mds/Map3k7tm1.1Mds Not Specified MGI:3696415


Genotype
MGI:3696415
hm1
Allelic
Composition		 Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k7tm1.1Mds mutation (0 available); any Map3k7 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:117108 )
• lethality in midgestation, at the same time as seen in Map3k7Gt(Betageo-ALPP)1Byg homozygotes

cardiovascular system
abnormal blood vessel morphology ( J:117108 )
• severe intraembryonic vascular defects
abnormal vitelline vasculature morphology ( J:117108 )
• severe yolk sac vascular defects

embryo
abnormal vitelline vasculature morphology ( J:117108 )
• severe yolk sac vascular defects




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory