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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptcratm1(icre)Hjf
targeted mutation 1, Hans Jorg Fehling
MGI:3696089
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptcratm1(icre)Hjf/Ptcratm1(icre)Hjf B6.129P2-Ptcratm1(icre)Hjf MGI:5505821


Genotype
MGI:5505821
hm1
Allelic
Composition		 Ptcratm1(icre)Hjf/Ptcratm1(icre)Hjf
Genetic
Background		 B6.129P2-Ptcratm1(icre)Hjf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptcratm1(icre)Hjf mutation (2 available); any Ptcra mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice
decreased double-positive T cell number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice

hematopoietic system
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice
decreased double-positive T cell number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice

endocrine/exocrine glands
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory