All Phenotypes Lyve1<tm1Lhua> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lyve1^tm1Lhua
targeted mutation 1, Jung S Huang
MGI:3697727

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lyve1^tm1Lhua/Lyve1^tm1Lhua	B6.129S1-Lyve1^tm1Lhua	MGI:3699230

Allelic Composition	Lyve1^tm1Lhua/Lyve1^tm1Lhua
Genetic Background	B6.129S1-Lyve1^tm1Lhua

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyve1^tm1Lhua mutation (1 available); any Lyve1 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymph circulation ( J:117713 )

• intradermally injected FITC-dextran moves away from the injection site more rapidly suggesting increased interstitial-lymphatic flow

lymphangiectasis ( J:117713 )

• vessels in the liver and intestine, but not in other tissues, display distended lumens with extended or round shapes

cardiovascular system

abnormal lymph circulation ( J:117713 )

• intradermally injected FITC-dextran moves away from the injection site more rapidly suggesting increased interstitial-lymphatic flow

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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