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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ts(1016)232Dn
trisomy, Chr 16 translocation to Chr 10, Davisson 232
MGI:3698134
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
Ts(1016)232Dn/0 involves: C3H/HeSnJ * C57BL/6JEiJ MGI:3706951


Genotype
MGI:3706951
ot1
Allelic
Composition
Ts(1016)232Dn/0
Genetic
Background
involves: C3H/HeSnJ * C57BL/6JEiJ
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phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• significantly more sperm with head abnormalities
• sperm concentration was significantly reduced below controls
• spermatogenesis was arrested at meiosis (prophase or metaphase I) in many tubules
• significantly reduced frequencies of sperm with progressive motility
• significantly smaller testes than controls
• produced no progeny
• fail to produce a vaginal plug

cellular
• significantly more sperm with head abnormalities
• sperm concentration was significantly reduced below controls
• spermatogenesis was arrested at meiosis (prophase or metaphase I) in many tubules
• significantly reduced frequencies of sperm with progressive motility

endocrine/exocrine glands
• significantly smaller testes than controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory