Phenotypes associated with this allele

• Allele Symbol: Ts(4¹⁷)2Lws
• Allele Name: trisomy 17, Chr 17 translocation to Chr 4, Lewis 2
• Allele ID: MGI:3698135
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Ts(4^17)2Lws/0	involves: C3H/HeSnJ * C57BL/6J * C57BL/6JEiJ * DBA/2J	MGI:3706957

Genotype
MGI:3706957

ot1

• Allelic Composition: Ts(4¹⁷)2Lws/0
• Genetic Background: involves: C3H/HeSnJ * C57BL/6J * C57BL/6JEiJ * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal male germ cell morphology ( J:117029 )

♂ • significantly more sperm with head abnormalities

arrest of male meiosis ( J:117029 )

♂ • spermatogenesis was arrested at meiosis (prophase or metaphase I) in many tubules

decreased sperm progressive motility ( J:117029 )

♂ • significantly reduced frequencies of sperm with progressive motility

decreased testis weight ( J:117029 )

♂ • significantly smaller testes than controls

male infertility ( J:117029 )

♂ • produced no progeny

♂ • fail to produce a vaginal plug

cellular

abnormal male germ cell morphology ( J:117029 )

♂ • significantly more sperm with head abnormalities

arrest of male meiosis ( J:117029 )

♂ • spermatogenesis was arrested at meiosis (prophase or metaphase I) in many tubules

decreased sperm progressive motility ( J:117029 )

♂ • significantly reduced frequencies of sperm with progressive motility

endocrine/exocrine glands

decreased testis weight ( J:117029 )

♂ • significantly smaller testes than controls