Phenotypes associated with this allele

• Allele Symbol: Asprv1^tm1Tmts
• Allele Name: targeted mutation 1, Takeshi Matsui
• Allele ID: MGI:3699318
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Asprv1^tm1Tmts/Asprv1^tm1Tmts	involves: 129S4/SvJae * C57BL/6	MGI:3699799

Genotype
MGI:3699799

hm1

• Allelic Composition: Asprv1^tm1Tmts/Asprv1^tm1Tmts
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Wrinkle formation in Asprv1^tm1Tmts/Asprv1^tm1Tmts mice

integument

abnormal coat appearance ( J:116504 )

• at 5 weeks of age, linear grooves running parallel to longitudinal body axis appear on the coat surface of homozygotes; these are enhanced when hind limbs are strctched backwards

wrinkled skin ( J:116504 )

• upon hair removal, numerous wrinkles are observed in skin of mutants, running parallel to the body, visible when mice are suspended by the tail

• all skin layers are present and there appear to be no defects in epidermal differentiation