Phenotypes associated with this allele

• Allele Symbol: Tg(CASP3)18Fine
• Allele Name: transgene insertion 18, Lorraine Kerr
• Allele ID: MGI:3699361
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CASP3)18Fine/?	involves: C57BL/6J	MGI:5140070

Genotype
MGI:5140070

tg1

• Allelic Composition: Tg(CASP3)18Fine/?
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased susceptibility to ischemic brain injury ( J:101696 )

• transgenic mice exhibit ischemic damage to the striatum after 30 min of middle cerebral artery occlusion; wild-type mice do not exhibit damage

• after 45 minutes of occlusion, most transgenic mice exhibit cortical damage

increased cerebral infarct size ( J:101696 )

• transgenic mice develop larger hemispheric lesions following middle cerebral artery occlusion than controls

nervous system

increased susceptibility to ischemic brain injury ( J:101696 )

• transgenic mice exhibit ischemic damage to the striatum after 30 min of middle cerebral artery occlusion; wild-type mice do not exhibit damage

• after 45 minutes of occlusion, most transgenic mice exhibit cortical damage

increased cerebral infarct size ( J:101696 )

• transgenic mice develop larger hemispheric lesions following middle cerebral artery occlusion than controls