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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm2(HIF1A/luc)Kael
targeted mutation 2, William G Kaelin
MGI:3699420
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Gt(ROSA)26Sortm2(HIF1A/luc)Kael/Gt(ROSA)26Sor+ involves: 129S6/SvEvTac MGI:3699516


Genotype
MGI:3699516
ht1
Allelic
Composition
Gt(ROSA)26Sortm2(HIF1A/luc)Kael/Gt(ROSA)26Sor+
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(HIF1A/luc)Kael mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• fusion gene is expressed ubiquitously; with tissue hypoxia, luciferase expression is enhanced in those tissues





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory