About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Furintm1.1Jwmc
targeted mutation 1.1, John W M Creemers
MGI:3700009
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Furintm1.1Jwmc/Furintm1.1Jwmc involves: 129P2/OlaHsd * BALB/c * C57BL/6J MGI:3700791
cn2
 		Furintm1Jwmc/Furintm1.1Jwmc
Tg(Mx1-cre)1Cgn/0 		involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6J * CBA MGI:3700792


Genotype
MGI:3700791
hm1
Allelic
Composition		 Furintm1.1Jwmc/Furintm1.1Jwmc
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Furintm1.1Jwmc mutation (1 available); any Furin mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:118515 )
• no homozygous embryos are recovered after E11.5




Genotype
MGI:3700792
cn2
Allelic
Composition		 Furintm1Jwmc/Furintm1.1Jwmc
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Furintm1.1Jwmc mutation (1 available); any Furin mutation (48 available)
Furintm1Jwmc mutation (0 available); any Furin mutation (48 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
liver/biliary system phenotype ( J:118515 )
N
• conditional mice show no liver phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory