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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Furintm1.1Jwmc
targeted mutation 1.1, John W M Creemers
MGI:3700009
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Furintm1.1Jwmc/Furintm1.1Jwmc involves: 129P2/OlaHsd * BALB/c * C57BL/6J MGI:3700791
cn2
 		Furintm1Jwmc/Furintm1.1Jwmc
Tg(Mx1-cre)1Cgn/0 		involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6J * CBA MGI:3700792


Genotype
MGI:3700791
hm1
Allelic
Composition		 Furintm1.1Jwmc/Furintm1.1Jwmc
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Furintm1.1Jwmc mutation (1 available); any Furin mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:118515 )
• no homozygous embryos are recovered after E11.5




Genotype
MGI:3700792
cn2
Allelic
Composition		 Furintm1Jwmc/Furintm1.1Jwmc
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Furintm1.1Jwmc mutation (1 available); any Furin mutation (48 available)
Furintm1Jwmc mutation (0 available); any Furin mutation (48 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
liver/biliary system phenotype ( J:118515 )
N
• conditional mice show no liver phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory