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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Igltm2Bgmn
targeted mutation 2, Marianne Bruggemann
MGI:3701068
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Igkctm1Bgmn/Igkctm1Bgmn
Igltm2Bgmn/Igltm2Bgmn 		involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA MGI:3702901


Genotype
MGI:3702901
cx1
Allelic
Composition		 Igkctm1Bgmn/Igkctm1Bgmn
Igltm2Bgmn/Igltm2Bgmn
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igkctm1Bgmn mutation (0 available); any Igkc mutation (9 available)
Igltm2Bgmn mutation (0 available); any Igl mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
arrested B cell differentiation ( J:118712 )
• development is blocked at pre-B-II to immature B cell transition stage
absent B cells ( J:118712 )
• IgM+ B cells are undetectable in spleens of mutants

immune system
arrested B cell differentiation ( J:118712 )
• development is blocked at pre-B-II to immature B cell transition stage
absent B cells ( J:118712 )
• IgM+ B cells are undetectable in spleens of mutants




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory